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It gets a bit more complicated when you move from providing flu vaccines to travel vaccines, on our Vaccine Courses we will always cover how to do this, but it takes practise! Some vaccines are supplied in a pre-filled syringe, others need to be reconstituted before use. Vaccines should be reconstituted when required, not in advance of an immunisation session, to avoid errors and maintain vaccine efficacy and stability.

To reconstitute…

…follow these simple steps to help you.

Only use the diluent supplied and note the time scale in which it must be used after dilution (often 1-4 hours)

A green needle (21G x 38mm (11/2 inch)) should be used to draw up the diluent and to inject it slowly into the ampoule containing the vaccine . Injecting diluent rapidly into the vaccine may cause frothing, which can affect the dilution and consequent potency of the vaccine; shaking the ampoule may have a similar effect
If the freeze-dried powder does not instantly dissolve in the diluent, gently rotate the ampoule until it dissolves.

Draw up the appropriate dose

Unless the vaccine is supplied in a pre-filled syringe with an attached needle, a new needle of a size appropriate to the individual patient should be used to inject the vaccine.

Extra information to consider:

When drawing up from a glass ampoule, use a needle gauge no larger than 21G to eliminate the possibility of drawing up glass fragments.
Where possible change a needle after it has passed through a rubber bung before administering the vaccine.

For quantities, less than 1ml use a graduated 1ml syringe
Appropriate infection control and aseptic techniques should be used at all times.

UK Needle Gauge and Length

 16mm or 25mm

Remember to always check back for more handy tips and information!

It is exciting times here at ECG and we are delighted with the new products and services we are able to offer you. Keep up to date with our latest news on our website, news and notices or simply give us a call in the office on 0845 423 8993.

Written by Jane Lambert, 24th May 2018